Are There Any Risk Factors For This Medication
Prednisone/prednisolone should not be used in pets that are allergic to it, or with systemic fungal infections , viral infections, ulcers, tuberculosis, or Cushings disease. It should be used cautiously in pets with diabetes, heart or vascular disease, other types of infections, osteoporosis, cataracts, high blood pressure, or kidney disease. Use prednisone/prednisolone cautiously in young animals as this medication can stunt growth. Extreme caution should be used when using prednisone/prednisolone in pregnant or lactating pets or in pets receiving medications that can cause ulcers.
Do not stop this medication abruptly taper it slowly to avoid complications.
Do not use in pets that are undergoing allergy testing within the next month, unless otherwise advised by your veterinarian.
Do not use the prednisone form in cats and horses, or in pets with liver dysfunction , as they cannot efficiently convert it to prednisolone.
What Are The Side Effects Of Prednisolone
Like all medicines, prednisolone can cause side effects, although not everyone gets them. Most side effects are related to the dose your child is taking and how long they are taking prednisolone for. Read more about taking steroids long term.
Prednisone Has Several Potential Side Effects That May Be Problematic
Robert Burakoff, MD, MPH, is board-certified in gastroentrology. He is the vice chair for ambulatory services for the department of medicine at Weill Cornell Medical College in New York, where he is also a professor. He was the founding editor and co-editor in chief of Inflammatory Bowel Diseases.
Prednisone is an inexpensive and effective corticosteroid drug that is frequently used to treat acute flare-ups of inflammatory bowel disease . While prednisone provides rapid relief, side effects are common and can occasionally be intolerable. These include insomnia, mood changes, abnormal hair growth, fatigue, thinning of the skin, and acne.
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What Is Prednisone/prednisolone
Prednisone/prednisolone is a glucocorticoid used to treat many conditions in many species. Broad uses include the following: replacement therapy for Addisons disease, an anti-inflammatory, an immune suppressant, and an antineoplastic . Although they are distinct drugs, prednisone is quickly converted to prednisolone in the liver, so they are considered bioequivalent .
While some products are labeled for use in some animals with certain conditions, its use in cats, dogs, horses, small mammals, birds, and reptiles to treat inflammation, immune-mediated disease, Addisons disease, and neoplasia is often off label or extra label. Many drugs are commonly prescribed for off label use in veterinary medicine. In these instances, follow your veterinarians directions and cautions very carefully as their directions may be significantly different from those on the label.
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How Much Is Too Much
Prednisone side effects largely depend on the dose you take, explains Kevin Deane, M.D., rheumatologist and researcher with the University of Colorado Health Rheumatology Clinic-Anschutz Medical Campus. Essentially, a low dose means fewer side effects, and a high dose means more side effects. It is helpful to have a mindset from the start that prednisone should only be used for low doses , says Dr. Deane.
How To Give Prednisolone
- Timing: How often to give prednisolone depends on what condition is being treated. It can be given once daily, several times a day or on alternate days. If your child is taking prednisolone once a day or on alternate days, it is best given at the same time each day, usually in the morning after breakfast. If your child is taking prednisolone several times a day, it is best if you give the doses evenly spaced throughout the day.
- Measuring the dose: Measure out the right amount using an oral syringe or medicine spoon, which you can get from your pharmacy. Do not use a household kitchen spoon because it does not give the correct amount.
- If your child is sick: If your child is sick less than 30 minutes after a dose of prednisolone, give the same dose again. But if they vomit and it is more than 30 minutes after a dose of prednisolone, they do not need to take another dose. Wait until the next normal dose.
- Stopping prednisolone: Continue to give prednisolone for as long as your doctor or pharmacist tells you. Some children may need a short course of prednisolone while others may need it for longer . If your child has been taking prednisolone regularly for longer than 2 weeks, do not stop it suddenly. Stopping suddenly can cause withdrawal symptoms, which can be serious or even life threatening. Instead your child will be given a tapering dose. This means their dose of prednisolone will be gradually reduced over a few days or weeks.
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Are There Any Potential Side Effects
The most common side effects include increased drinking, increased urination, and increased appetite. At higher doses and during long-term use, side effects may also include vomiting, diarrhea, mild behavioral changes, and panting. Serious side effects include gastrointestinal ulceration characterized by a lack of appetite, black or bloody stools, bloody vomit, or high fever, as well as haircoat changes, pot belly, weight gain, weakness, liver and lipid elevations, aggressive behavior, muscle wasting, abnormally low energy, or diabetes characterized by weight loss in the face of good appetite, excessive thirst and urination.
This short-acting medication should stop working within 24 hours, although effects can be longer in pets with liver or kidney disease.
What Happens If I Overdose
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
An overdose of prednisone is not expected to produce life threatening symptoms. However, long term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat , increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.
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Prednisone Use In Children
Children taking prednisone are of special concern and require careful consideration. A childâs growth rate may be impaired, ultimately resulting in the delay of puberty. Children taking prednisone for any length of time should be monitored closely for any signs of long-term side effects such as impaired growth.
To avoid growth impairment in children, smaller prednisone dosages are often recommended. Dosing every other day may also help.
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How To Discontinue Prednisone
Care must be taken when lessening the dosage of prednisonea patient should not stop taking it suddenly. The body stops or decreases its own production of cortisol, and slowly tapering the amount of prednisone taken daily allows the body to begin producing it again on its own.
Tapering the dose of prednisone means lowering the dose by a certain amount every few days or every week. The length of time to taper will depend on the starting dosage, and the amount of time the prednisone has been taken. At higher dosages taken for a long period of time, it may take months to taper down. A short course can be tapered down relatively quickly.
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Are There Any Safer Steroid Alternatives
There are steroids that you can take without getting the same side effects.
In the cause of my research for this post, I discovered safer and legal replacements. These are supplements manufactured by CrazyBulk, a company that produces steroids alternatives.
According to the manufacturer, these steroids are not only safe but also legal and will not cause any side effects such as diarrhea.
Some of their products include:
- D-bal and used for gaining lean muscle mass
- Trenorol is used for cutting, bulking, and strength
- Testo-Max is used to increase testosterone levels in men naturally
- Anadrole and used to boost red blood cell production and increase muscle mass
- Clenbutrol is used as a powerful fat burner
- Winsol and used for cutting cycles, preserving lean muscle mass, and strength
- Anvarol is used for cutting cycles, preserving lean muscle mass and strength
- is used to increase protein synthesis in the body
Guideline / Expert Opinion
The Oncology Nursing Society is a professional association that represents 100,000 nurses and is the professional home to more than 35,000 members. ONS is committed to promoting excellence in oncology nursing and the transformation of cancer care. Since 1975, ONS has provided a professional community for oncology nurses, developed evidence-based education programs and treatment information, and advocated for patient care, all in an effort to improve the quality of life and outcomes for patients with cancer and their families.
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When To Contact A Doctor
Let a doctor know about new or worsened UC symptoms. Also, never take leftover prednisone without first talking with a doctor.
A doctor can provide detailed instructions about when and how to take prednisone. They can also monitor how it affects UC symptoms and check for side effects.
Prednisone is only suitable for short-term use, and taking it for too long increases the risk of complications, including severe
Keep Your Pet Safe Long
The typical goals of asthma management are risk reduction and symptom control. According to the Global Initiative for Asthma 7, the intent of management is to reduce the burden to the patient and to reduce their risk of asthma-related death, exacerbations, airway damage, and medication side-effects.
In human children with asthma, inhaled steroids are considered the gold standard treatment for long term disease management. Systemic steroids are not recommended for daily asthma control. And, just like for children, inhaled steroids are considered safe and effective for cats and are a better option for the management of respiratory conditions.8
For cat owners, being informed about the side effects of injected and oral corticosteroid use is the first step in ensuring your cat is safe and healthy. Always be on the lookout for any side effects your cat may be showing after starting these medications.
Before starting your cat on oral steroids or if you are interested in transitioning away from systemic steroids, talk with your vet about using inhaled corticosteroid medications instead, and how the AeroKat* chambercan help manage your cats condition.
Is There Any Monitoring That Needs To Be Done With This Medication
Monitoring recommendations will vary depending on the reason for use, the dosage, duration of therapy, and your pets health status. Common monitoring includes bloodwork and urinalysis, blood sugar levels, ACTH stimulation tests, weight and appetite status, signs of swelling, and serious side effects. Your veterinarian may monitor your pet to be sure that the medication is working.
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Help support the Sjögren’s Foundation by donating today! Not only will your donation help fund critical research, educational opportunities and support the Foundation’s mission to create ‘a community where patients, healthcare professionals, and researchers come together to conquer the complexities of Sjögrens’ but it is also 100% tax deductible.
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What Other Drugs Will Affect Prednisone
Many drugs can interact with prednisone. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with prednisone, especially:
an antibiotic such as clarithromycin or telithromycin
antifungal medication such as itraconazole, ketoconazole, posaconazole, voriconazole
birth control pills and other hormones
a blood thinner such as warfarin, Coumadin
a diuretic or “water pill”
the hepatitis C medications boceprevir or telaprevir
HIV or AIDS medicine such as atazanavir, delavirdine, efavirenz, fosamprenavir, indinavir, nelfinavir, nevirapine, ritonavir, saquinavir
insulin or diabetes medications you take by mouth
a non-steroidal anti-inflammatory drug such as aspirin, ibuprofen , naproxen , celecoxib, diclofenac, indomethacin, meloxicam, and others
seizure medications such as carbamazepine, fosphenytoin, oxcarbazepine, phenobarbital, phenytoin, primidone or
the tuberculosis medications isoniazid, rifabutin, rifapentine, or rifampin.
This list is not complete and many other drugs can interact with prednisone. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.
What Are The Possible Side Effects Of Prednisolone
Prednisolone helps most people who take it, but some people experience side effects.
Generally, the risk of side effects is low if you take prednisolone for a short time. Your risk increases if you take high doses of prednisolone for a long time.
Common side effects of prednisolone, especially with high doses for long periods, include:
- fluid retention, which can lead to heart problems
- symptoms such as severe dizziness, fainting, weakness, chest pain or irregular heart beat
- mental disturbances
It is important to take prednisolone as prescribed. Talk with your doctor if you would like to lower your dose or stop taking prednisolone. Stopping it suddenly might cause serious side effects and can be dangerous.
This is not a full list of side effects. For more information about the risks of side effects, read the Consumer Medicines Information for the brand of prednisolone you are taking or speak to your doctor or pharmacist.
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Changes In Blood Sugar Levels
You might have regular blood and urine tests to check this. Some people develop diabetes. You might need to have blood sugar lowering treatment. But your sugar levels usually go back to normal shortly after you stop taking steroids.
If you have diabetes already, you might need to check your blood sugar levels more often than usual.
Will Prednisone Affect My Sleep
Insomnia can be a frustrating side effect of prednisone use since the drug can alter the natural balance of sleep-regulating chemicals in the body. If it gets really bad, you can talk with your doctor about adding a sleeping medication to your arsenal. That said, taking your prednisone dose in the morning can do the trick to help you avoid disrupted sleep, says Dr. Tarrant. Thats when our normal steroid hormone naturally peaks, she says. If you take it at night, its going to disrupt the sleep-wake cycle.
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What Are The Long Term Effects Of It
Dogs who take Prednisone may experience both short-term and long-term negative effects. Even when the medication is discontinued, the long-term effects continue.
Long term effects of Prednisone:
Consumer Information Use And Disclaimer
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How Fast Does It Work
Prednisone can have a positive effect on acute severe and sudden UC symptoms. The drugs powerful anti-inflammatory properties mean that it can help control stomach pain, diarrhea, and bloody stools, among other symptoms.
According to The Arthritis Society, prednisone usually works within 14 days if a person takes the appropriate dosage. But some people may experience symptom relief within just a few hours. How quickly it works depends on how a person takes it and whether the drug is formulated for immediate or delayed release.