Epidemiology Of Ibs And Ibdboth On The Rise In Asia
The incidence of CD in the world ranges from 5.0 to 10.7 per 100,000 person-years, while the incidence of UC ranges from 6.3 to 24.3 per 100,000 person-years. The marked variations are due to geographical localities, with Asia tending to show the lowest incidence rate, as compared to predominantly UC in Europe, and CD in North America.5 Even in Asia, with its large geographical area, there is variation in the annual incidence rate from 0.1 to 6.3 per 100,000 population for UC and 0.04 to 5.0 per 100,000 population for CD.5
Gender differences were reportedly equal in large population-based studies, although some contested a higher male preponderance for IBD in Asia.5,6 The highest incidence ages of diagnosis were recorded in the second to fourth decades, therefore implicating the most productive age group, with socioeconomic impact in terms of hours off work and impaired productivity.
IBS in Asia shows a prevalence rate of 2.9% to 15.6%, with no predilection for the traditionally female gender.7,8,9 The prevalence rate is highly dependent on the utilization of Manning or Rome-based criteria, and to a lesser extent on the geographical distribution. Age distribution still involves younger individuals in their early 20’s, comparable to Western studies.
However, for both IBS and IBD, the prevalence and annual incidence has shown a consistently increasing trend in Asia which is in keeping with a worldwide trend.
Common Questions & Answers
While no two people will experience Crohn’s disease in the same way, most have diarrhea and abdominal pain or cramping. Other common symptoms include rectal bleeding, nausea, loss of appetite, an urgent need to use the bathroom, and constipation.
Weight loss, fatigue, joint pain, red or itchy eyes, and inflamed or bumpy skin may also occur.
There is no single diet for Crohn’s disease. However, common triggers you may want to avoid include whole grains, nuts and seeds, raw fruits and vegetables, spicy foods, fatty or greasy foods, dairy products, and caffeinated and alcoholic beverages.
During a flare, when symptoms are at their worst, it may be helpful to stick to bland, soft foods.
The first step in testing for Crohns is a physical exam, a full medical history, and tests to rule out other conditions, including lactose intolerance, irritable bowel syndrome, and ulcerative colitis.
Blood tests, stool tests, colonoscopy, upper GI endoscopy, wireless capsule endoscopy, and imaging tests are also used to diagnose Crohn’s.
Signs And Symptoms Of Crohns Disease
No two people experience Crohns disease in exactly the same way.
Your symptoms will depend on what areas of your bowel are affected, as well as how advanced your disease is and how well your treatments are working.
Most people with Crohns disease experience inflammation in both their small intestine and their large intestine , which often causes diarrhea and abdominal pain or cramping.
Other common digestive symptoms include rectal bleeding, nausea or loss of appetite, an urgent need to defecate, and constipation.
Crohns disease can also cause weight loss, fatigue, and symptoms outside the digestive system, like joint pain, red or itchy eyes, and inflamed or bumpy skin.
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Living With The Diseases
Will I need to have surgery or can I simply take medications instead?Medications are usually the first line of treatment. If medical management is unsuccessful, surgery is an effective option to cure UC. Surgery might be needed to treat Crohns complications, such as strictures , abscesses , or fistulae .
Are the medicines used to treat Crohns disease or UC expensive?Some medications can be expensive, but many pharmaceutical companies offer financial assistance programs that help reduce the out-of-pocket expenses.
Do I have to observe special precautions while on medications for Crohns disease or UC?Patients taking specific classes of medications can be more prone to infections. Patients on these medications should take standard precautions such as hand washing, especially if they have contact with people who are sick with a cold, the flu, or other contagious diseases. We also recommend paying attention to current vaccination recommendations, such as flu and pneumonia vaccines.
Should I be taking food supplements or over-the-counter vitamins?These products are generally not thought to lessen or prevent disease, but supplements might be recommended if lab work indicates a deficiency.
When should I call my physician about a change in my symptoms?You should contact your physician if the pain level increases, diarrhea worsens, or you notice more blood in your stool. Medication changes might be needed or, if symptoms are severe, you may need to be hospitalized.
Q What Are The Symptoms Of Ibs And Ibd
Both are digestive conditions and affect the esophagus, stomach and intestines. IBS is a chronic syndrome made up of a group of symptoms. IBD, on the other hand, refers to inflammation or chronic swelling of the intestines.
IBS symptoms include chronic abdominal pain and changes in bowel habitsdiarrhea and constipation, or alternating between both. Symptoms can vary person to person and can often change over time, making it difficult to manage.
IBS does not develop into IBD or cause permanent harm in your intestines, such as intestinal bleeding, other intestinal diseases or cancer. But it can significantly affect your quality of life. Some have reported they would be willing to give up their essential pleasurescaffeine, use of cell phone and the internet and even sex to be free of IBS symptoms.
Common forms of IBD include Crohns disease and ulcerative colitis. Both cause chronic inflammation in the GI tract. These conditions can cause rectal bleeding and diarrhea, bloating, abdominal cramping, pain, reduced appetite, unintended weight loss and fatigue.
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Myth: Cutting Out Dairy And Gluten Can Get Rid Of Ibs Symptoms Since Ibs Is Just Another Term For These Intolerances
Reality: Some individuals with IBS do have intolerances to the milk-sugar, lactose, and some might have gluten intolerance as well. There are also people who do not have IBS but who do have these intolerances. Lactose intolerance is rare in people of Northern European descent, whose ancestors have historically consumed large quantities of dairy. Approximately 5% of these people are lactose intolerant. However, in people of East Asian descent, it is extremely common, with up to 90% being lactose intolerant. Lactose intolerance is also fairly common in those of West African, Jewish, Italian, Greek, and Arab descent.1 Overall, an estimated 16% of Canadians are lactose intolerant.2 Gluten intolerance, which is not the same thing as celiac disease, is less common, affecting approximately 3-6% of the population.3 In some individuals with IBS, removing these foods can reduce or eliminate symptoms. In most of the Canadian population, these foods cause no problems at all because they are not lactose or gluten intolerant. IBS is a distinct disorder with its own diagnostic criteria and neither lactose intolerance nor gluten intolerance are on the list.
Ibd And Ibs Treatment
People who have IBD or IBS often try to treat it by changing what they eat. Thereâs no specific diet that works for everyone. Ask your doctor if it would help to:
- Get more fiber .
- Avoid lactose, which is in dairy products.
- Cut down on foods that make you gassy or bloated.
- Get more water.
- Avoid caffeine and legumes .
- Limit or avoid FODMAPs, a type of sugar found in some fruits, vegetables, breads, and dairy products.
Doctors usually treat IBD with drugs that target the inflammation:
- Aminosalicylates work on the lining of your intestine. They help in mild or moderate cases of IBD.
- Corticosteroids weaken your immune system. Youâll take them for a short time if your symptoms flare up.
- Immunomodulators also affect your immune system. You can use them as a long-term treatment.
- Biologic therapies keep proteins in your body from causing inflammation.
- Antibiotics fight infection caused by the disease or from surgery to treat it.
These meds generally donât work for IBS, which is one reason why itâs so important to know which condition you have.
Some people who have IBD need surgery to repair the damage to their digestive tract, but those with IBS donât.
If you have IBS, your doctor may recommend over-the-counter or prescription drugs to help with diarrhea or constipation. These include laxatives or anti-diarrheals, antispasmodics, and antidepressants.
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Do Corticosteroids Cause Side Effects In Dogs
Corticosteroids are notorious for causing a variety of side effects in humans. The typical increased drinking, urination, and appetite are often seen at the beginning, and long-term use can affect the liver. To minimize any possible adverse effects, the goal is to use the lowest effective dose and to give it on an every-other-day schedule. It will be necessary to begin therapy with a high dose, but once a response to the medication occurs, the dose is gradually tapered to the minimum effective dose.
How Is Ibd Treated
Several types of medicines may be used to treat IBD. Some vaccinations are also recommended for patients with IBD to prevent infections. For some patients, surgery may be required to remove damaged portions of the GI tract, but advances in treatment with medicines mean that surgery is less common than it was a few decades ago. Since Crohns disease and ulcerative colitis affect different parts of the GI tract, the surgical procedures are different for the two conditions.
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Ibd Vs Ibs: Understanding Different Gastrointestinal Conditions
Irritable bowel syndrome and inflammatory bowel disease are two distinct gut disorders. While very different in nature, they are often confused due to their similar-sounding names and several overlapping symptoms.
Although there are many distinctions between the two, one key differentiator is that IBD involves swelling of the intestines, whereas IBS does not. These conditions require very different treatments, and as such, an accurate diagnosis is vital to ensure proper management.âRead on to learn more about IBD and how it differs from IBS.â
Protecting Your Mental Health
If you experience any changes in your mood or symptoms of depression, seek help from a doctor or mental health professional. Treatments are available to help you manage your mental health along with your GI symptoms.
- International Foundation for Gastrointestinal Disorders has resources and personal stories of people living with GI disorders.
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Q What Are The Causes Of Ibs And Ibd
Researchers are still working to understand the exact causes. Some people develop IBS after a GI infection. Other potential causes include diet, environmental or psychological factors, such as stress, and frequent use of antibiotics.
With IBD, stress may worsen the condition and studies suggested that your genes, immune system and environmental factors may also play a role. Those with IBD are known to have an overactive immune system, which causes inflammation in the GI tract.
Myth: Ibs Isnt A Big Deal
Reality: Some individuals might have mild symptoms, but for others, IBS can change their entire life. The impact of the ABCD symptoms that constitute IBS can lead to a huge decrease in quality of life. Persistent diarrhea can make those affected afraid to leave home unless they are positive that they will have continuous access to a toilet. Chronic constipation can cause such intense pain and bloating that those affected are unable to get out of bed, as any type of physical movement, including sexual activity, causes intense pain. Symptoms like these can lead to social isolation and missed work or school that, in turn, can increase depression and other mental health symptoms.
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Ibd Is Not Celiac Disease
Celiac disease is another condition with similar symptoms to IBD. However, the cause of celiac disease is known and is very specific. It is an inflammatory response to gluten, a group of proteins found in wheat and similar grains. The symptoms of celiac disease will go away after starting a gluten-free diet, usually after a few months.
Does This Mean That I Will Be Giving Steroids To My Dog For The Rest Of His Life
Long-term therapy may be necessary for most dogs diagnosed with IBD. Generally, a dog is treated for a few months, then the medication is discontinued to see if it is still needed. If vomiting or diarrhea recurs, treatment is resumed. If oral medications are difficult to administer, it may be possible to give periodic injections of the long-acting corticosteroid, methylprednisolone . The disadvantage of long-acting injections is that once the medication is administered, it cannot be removed from the body if there are any problems.
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Where Is Ibs And Ibd Pain Normally Located
In IBS, the pain is usually spread over a wider area of the abdomen but is usually located in the lower half. In IBD, the pain can occur anywhere in the abdomen, and its location may suggest the type of IBD you have. Crohn’s disease usually causes pain in the lower right side of your belly. The other primary type of IBD, ulcerative colitis, leads to pain in the left side of your abdomen.
Symptoms Versus Inflammation Mismatch
Inherently, IBD is an organic disease, as evidenced by mucosal inflammation, whereas IBS lies more in the spectrum of a functional disorder, with no evidence of organic disease. IBS symptoms are nonspecific, and may precede diagnosis of both IBS and IBD by many years. Lack of mucosal inflammation results in a mismatch compared to the severity of the reported symptoms.
In IBD, mucosal inflammation is characteristic, but the symptoms do not necessarily correlate with endoscopic findings.51
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Fecal And Mucosal Sample Collections
A total of 107 fecal samples were included in this study and processed, specifically 30 from IBD patients, 36 from IBS patients, and 41 from CTRLs .
A total of 142 biopsy specimens were obtained from 126 subjects. Specifically, 45 biopsies from CTRLs, 44 from IBS patients and 53 from IBD patients were collected.
What Is Crohns Disease Symptoms Causes Diagnosis Treatment And Prevention
Crohn’s disease is a chronic digestive disorder that causes inflammation and damage in the digestive tract.
The disease belongs to a group of conditions called inflammatory bowel diseases .
There’s no cure for Crohn’s disease, but there are many treatments to help manage its symptoms.
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Experience You Can Count On
Our Inflammatory Bowel Disease Program specializes in diagnosing, treating and managing IBD and its symptoms. Patients receive highly personalized care from board-certified gastroenterologists with extensive experience in inflammatory bowel diseases.
Our specialties include:
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Pinpoint diagnosis We are committed to understanding and identifying the cause, location and severity of your IBD. Our team will conduct a complete exam, including taking a detailed personal and family history. We may order additional tests, such as CT scans or colonoscopies.
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Individualized treatment Your team is committed to creating a treatment plan that is tailored to the location and severity of your inflammatory bowel disease. Our team will monitor your progress and condition and adjust your plan as needed.
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Latest advances in care Temple surgeons are leaders in minimally invasive surgery and lead the way with the newest approaches in care.
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Clinical trials Temple University Health is part of a leading academic center and participates in the latest research and clinical trials to advance care for inflammatory bowel disease.
Ibs Vs Ibd: Two Very Different Illnesses
It is of vital importance to distinguish these two very different gut conditions. While both are chronic, the overall treatment and prognosis are very different. There are other important considerations. Because so may people have IBS, it is not surprising that some will also acquire IBD. That is, they may occur in the same patient due to chance. It is therefore crucial that the IBS symptoms in these patients not be confused with those due to IBD. The powerful, often expensive, sometimes-toxic drugs employed to treat IBD will not improve IBS symptoms. There are many reported instances where IBD has been misdiagnosed as IBS for years until finally the diagnosis is made. A more likely explanation is that IBS was present first and the IBD started later.
Finally, both IBD and IBS may be mistaken for other diseases such as appendicitis, diverticulitis, and chronic gut infections. Careful attention to the medical history and a thorough physical examination should avoid any such confusion.
Both IBD and IBS trouble many people. However, because of its propensity to damage the gut and other organs, IBD may produce disfigurement and sometimes-permanent physical disability. While there is no doubt IBS patients can suffer greatly from symptoms, their outlook is better than those who have IBD. A perusal of Table 1 illustrates many important reasons to distinguish the two conditions.
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Is There A Connection Between Ibs And Colitis
Colitis is defined as inflammation in the large intestine. It can be caused by many things, including:
- Autoimmune disease
- Lack of blood supply
- Other serious conditions
Colitis can result in symptoms that are similar to those of irritable bowel syndrome . This raises the question: Is there an overlap or connection between IBS and colitis?
Fecal And Mucosal Microbiota Profiling In Irritable Bowel Syndrome And Inflammatory Bowel Disease
- 1Department of Infectious Diseases, Istituto Superiore di Sanità , Rome, Italy
- 2Gastrointestinal Unit, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy
- 3Human Microbiome Unit, Bambino Gesù Childrens Hospital, IRCCS, Rome, Italy
- 4Unit of Digestive Disease, Campus Bio-Medico University, Rome, Italy
- 5Unit of Medical Statistics and Molecular Epidemiology, Campus Bio-Medico University, Rome, Italy
- 6Unit of Clinical Laboratory Science, Campus Bio-Medico University, Rome, Italy
- 7Human Microbiome Unit and Parasitology Unit, Bambino Gesù Childrens Hospital, IRCCS, Rome, Italy
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