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What Is Ondansetron 4 Mg Used For
Ondansetron is used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery. Ondansetron is in a class of medications called serotonin 5-HT3 receptor antagonists. It works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting.
Does Drinking Water Really Help With Heartburn
Watera cure for heartburn? The first thing youll want to do when youre awakened by heartburn pain is to stand up. Drink a whole glass of water, and follow it with a mixture of 1 tablespoon of baking soda, and half a glass of water. DONT drink milk or suck on mints to relieve heartburn. More items
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Which Antacids Are Safest To Take
Antacids that have magnesium oxide or magnesium hydroxide are also safe choices. Both calcium and magnesium-based antacids work by neutralizing the acid in your stomach, which helps reduce pain and discomfort. In severe heartburn cases, your doctor may suggest an H2 blocker, which decreases the amount of acid in your stomach.
Does Zofran Calm You Down
Ondansetron showed greater therapeutic efficacy at alleviating symptoms of overall mood disturbance, fatigue, vigor, confusion/bewilderment, and depression among EOA compared with LOA. EOA-associated improvements in mood disturbance seemed to be independent of drinking behavior.
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Heartburn And Gerd: How To Treat Nausea And Stomachaches
If you ever feel a burning sensation rise from your stomach into your chest and throat after a meal, youre far from alone. More than 60 million Americans experience the discomfort of heartburn at least once a month, according to the American College of Gastroenterology.
We created this guide to better help you understand what heartburn is, and most importantly, how you can fix it. The good news is, there are plenty of effective treatment options available to help ease and prevent the burn and discomfort. Be it using over-the-counter or prescription medications, or making a few lifestyle changes, weve got you covered.
What You Should Know Before Taking Antacids
Before taking antacids you should know that antacids decrease the acidity of the acids in your stomach. In the short term this is a very safe medication, which can help eliminate discomfort. However, as with all medications there are side effects with long term use, as the acidity of your stomach is changed.
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What Are Ondansetron And Metoclopramide
Ondansetron is an anti-nausea medication used to prevent nausea and vomiting that results from cancer chemotherapy. Chemotherapy agents cause increased secretion of serotonin, which stimulates serotonin receptors in the brain, resulting in nausea and vomiting. Ondansetron works by selectively blocking serotonin receptors, thereby reducing the effect of increased serotonin due to chemotherapy. It is also prescribed for prevention of nausea and vomiting after surgery.
Metoclopramide is a “prokinetic” drug that stimulates the muscles of the gastrointestinal tract including the muscles of the lower esophageal sphincter, stomach, and small intestine by interacting with receptors for acetylcholine and dopamine on gastrointestinal muscles and nerves. It is used in adults to relieve heartburn symptoms with gastroesophageal reflux when certain other treatments do not work and to relieve the symptoms of slow stomach emptying in people with diabetes.
Why Treat Heartburn And Acid Reflux During Pregnancy
Heartburn and acid reflux are traditionally considered innocuous because they are common in pregnancy and are usually self-limiting. However, a recent study suggests that GERD is associated with an increase in the severity of nausea and vomiting of pregnancy , which can have serious negative effects on a womans quality of life. In a prospective cohort study conducted by the Motherisk Program, 194 pregnant women with NVP and heartburn or acid reflux were compared with 188 pregnant women with NVP who did not have heartburn or acid reflux. The 2 groups were assessed for severity of NVP with the pregnancy-unique quantification of emesis and nausea score, which is a validated scoring tool based on frequency and duration of nausea, vomiting, and retching in the past 24 hours, with a high score indicating more severe NVP. Quality of life was measured by the well-being score, with 0 being the worst and 10 being the best. Forty-eight percent of women in the control group had severe NVP according to the PUQE, compared with 75% in the group with heartburn and acid reflux. The mean well-being score in the control group was significantly higher than that in the group with heartburn and acid reflux .
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Rated For Alcohol Dependence Report
This is a miracle drug. Without it I would not be able to eat due to chronic nausea. For me the headaches are minimal and a couple of aspirin take care of it The trade-offs between weighing less than 100 pounds because I cant hold food down, vrs being nauseous 24 seven versus an occasional headache, the benefits far outweigh the negatives Other than constipation and the occasional headache which again, an aspirin takes care of, this drug has had no additional side effects
What Happened To Mylanta
For many years, especially in the 1990s, Mylanta was a popular product used to alleviate the symptoms of heartburn. However, in 2010, the over-the-counter antacid was voluntarily recalled due to traces of alcohol being found in the product.
According to the manufacturer, Johnson & Johnson, the product was recalled so it could be relabelled with better accuracy, not because of any risk to alcohol absorption or adverse effects.
In 2016 Mylanta was reintroduced to the market and deemed safe to use as an antacid.
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Gerd: Heartburn And More
ARCHIVED CONTENT: As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date each article was posted or last reviewed. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.
Doctors call it gastroesophageal reflux disease, or GERD. Millions of men call it heartburn, and many others have coughing, wheezing, or hoarseness without realizing that GERD is to blame. By any name, GERD is common, bothersome, and sometimes serious. It is also expensive, draining the American economy of more than $9 billion a year. But once you know you have GERD, you can control it and prevent complications.
How Should I Give It
Ondansetron may be given by mouth as a liquid, pill, or tablet or in a vein . It may be given in one of these ways:
- as needed
- at regular times
- continuously through an IV
Your child should be awake and alert when taking any medicine by mouth. Follow the checked instructions below:
___ If using the liquid form, draw up the correct amount in the medicine dropper or oral syringe. Give a small squirt of the medicine inside the cheek. To avoid choking, let your child swallow each squirt before giving more.
___ For babies, you may want to mix the medicine with a small amount of formula or breast milk and give it with a bottle nipple before feeding. Do not add the medicine to a whole bottle because if your baby does not finish it, you will not know how much of the medicine was taken.
___ For older children who cannot swallow pills, a special tablet called Zofran ODT is available. Place it under the tongue and it will dissolve.
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Getting The Most From Your Treatment
- Ondansetron should start to work within an hour or so. If you are taking tablets or liquid medicine and you are sick within one hour of taking a dose, you should take the same dose again. This does not apply, however, if you are using suppositories or if you have been given an injection, as being sick will not prevent these from being absorbed by your body.
- Even if you do not feel like eating or drinking, try to sip water regularly to prevent you from becoming lacking in fluids . Also, rather than trying to eat three main meals a day, try eating small, simple but nourishing snacks, every few hours.
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A New Approach To Managing Gastroparesis
Manouchehr Saljoughian, PharmD, PhDAlta Bates Summit Medical CenterBerkeley, California
US Pharm. 2019 44:32-34.
Gastroparesis is a chronic disorder that affects a significant subset of the population. Ordinarily, strong muscular contractions move food through the digestive tract. In gastroparesis, this mechanism is disrupted, and undigested food stays in the abdomen for a long time and makes a person feel nauseous with the urge to vomit. Gastroparesis can also cause a lack of appetite, which may lead to malnutrition, and patients who are not eating can expect discomfort, bloating, and heartburn.1
The pathophysiology behind gastroparesis is varied and depends on disease etiology. Vagal and/or autonomic neuropathy play an important role in the development of diabetic gastroparesis, and it is estimated to occur in up to 20% to 40% of patients with diabetes. Gastroparesis can cause problems with blood sugar levels and nutrition. Sometimes, it is a complication of diabetes, and some people may develop gastroparesis after surgery. Although there is no cure for gastroparesis, changes to the diet, along with medication, can offer some relief.1,2
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Typical Dosing For Zofran
Chemotherapy that causes severe nausea and vomiting: a single 24 mg dose taken 30 minutes before the start of a single-day highly vomit-inducing chemotherapy.
Chemotherapy that causes moderate nausea and vomiting: 8 mg dose taken 30 minutes before the start of chemotherapy, with another 8 mg dose taken 8 hours after the first dose. Take 8 mg twice a day for 1 to 2 days after completing chemotherapy.
Radiation therapy: 8 mg dose taken 1 to 2 hours before radiation therapy. Depending on the type of radiation therapy and location of radiation therapy, 8mg dose can be taken every 8 hours after the first dose for each day radiation therapy is given or for 1 to 2 days after completing radiation therapy.
After surgery : 16 mg dose taken 1 hour before starting anesthesia.
- Chemotherapy that causes moderate nausea and vomiting: 8 mg dose taken 30 minutes before the start of chemotherapy, with another 8 mg dose taken 8 hours after the first dose. Take 8 mg twice a day for 1 to 2 days after completing chemotherapy.
- Chemotherapy that causes moderate nausea and vomiting: 4 mg dose taken 30 minutes before the start of chemotherapy, with another 4 mg dose taken 4 and 8 hours after the first dose. Take 4 mg three times a day for 1 to 2 days after completing chemotherapy.
Coronavirus In The Gut: Gi Manifestations Mechanism And Medications
The novel coronavirus can cause gastrointestinal symptoms such as nausea, vomiting and diarrhea.
Patient: Doc, I get heartburn every time I eat birthday cake.
Gastroenterologist: Next time, remove the candles.
In a medical specialty about the gut, bloating and pooping, jokes pretty much write themselves. But for many people struggling with gastrointestinal symptoms and Covid-19 infection, life is far less funny. And right now, the coronavirus pandemic shows no signs of slowing down. Amid nationwide protests following the murder of Mr. George Floyd, Covid-19 cases and deaths in the U.S. are rising steadily, now at 1.98 million and 112,000, respectively.
As coronavirus unnervingly looms, we continue to learn more about this novel SARS-CoV-2 pathogen. For instance, stomach ache and diarrhea may be the first signs of the infection, as Robert Glattner, MD discussed in March. Since that time, weve gained additional information about the COVID Gut both in adults and in children, as well as its mechanism of action and treatment options.
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How To Prevent Medication
Not everyone will become constipated when using these medications. However, you should be aware of the possible side effects and what you can do to prevent constipation.
In general, you want to make sure you are well hydrated with water, not coffee or carbonated beverages, says Dr. Curtin. You also want to have a healthy amount of fiber in your diet and try to limit processed foods. It is worth asking your doctor if there are alternative agents. Calcium channel blockers, used for high blood pressure, such as diltiazem, for example, are notorious for causing constipation. If there is another class of medication that can treat the underlying health problem, you should at least be given the option.
Fortunately, there are some relatively simple nonpharmacologic approaches to preventing constipation.
What Is In This Leaflet
Please read this leaflet carefully before you start taking Zofran Zydis wafers.
This leaflet answers some common questions about Zofran Zydis wafers. It does not contain all of the available information.
It does not take the place of talking to your doctor or pharmacist.
All medicines have risks and benefits. Your doctor has weighed the risks of you taking Zofran Zydis wafers against the benefits this medicine is expected to have for you.
If you have any concerns about taking this medicine, ask your doctor or pharmacist.
Keep this leaflet with the medicine.
You may need to read it again.
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What Is The Dosage Of Ondansetron Vs Metoclopramide
Dosing for adults:
- Highly nauseating chemotherapy: 24 mg orally dissolved on tongue 30 minutes prior to start of a single-day chemotherapy.
- Moderately nauseating chemotherapy: Take 8 mg tablet 30 minutes prior to chemotherapy and repeat in 8 hours, then 8 mg every 12 hours for 1 to 2 days after chemotherapy.
- Radiation-induced nausea and vomiting: Take 8 mg orally 1 to 2 hours prior to radiation and every 8 hours after first dose, as needed.
- Post-surgery nausea and vomiting: 16 mg orally 1 hour before anesthesia.
Dosing for children:
- Moderately nauseating chemotherapy : 8 mg orally prior to chemotherapy and repeat in 8 hours, then 8 mg every 12 hours for 1 to 2 days after chemotherapy.
- Moderately nauseating chemotherapy : 4 mg orally 30 minutes prior to chemotherapy and repeat in 4 and 8 hours after the first dose, then every 8 hours for 1 to 2 days after chemotherapy.
- Not recommended for children under 4 years old.
The usual dose of metoclopramide for treating GERD is 10-15 mg four times daily, 30 minutes before each meal.
Gastroparesis is treated with 10 mg administered orally four times daily, 30 minutes before each meal and at bedtime.
How To Choose A Product:
- Determine what is most important to you: cost , formulation , time to have an effect , quality of the product , etc
- Some products labeled gluten-free actually have gluten in them, because they still meet the FDA definition which allows for up to 20 parts per million.
- Look at the source of the flavors and dyes to ensure safety during pregnancy
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The Best Types Of Medicine For Nausea And Which Is Right For You
- Nausea medicine can be helpful if you’re pregnant, have acid reflux, or are susceptible to motion sickness.
- Here’s the best nausea medicine to take in each case and what you should know about the side effects.
There are many different reasons why you may experience nausea. Sometimes it is due to an underlying medical condition. Other times, nausea may occur as a result of motion sickness or eating too much.
In many of these cases, taking anti-nausea medication can help relieve your symptoms quickly. But which medicine you should take depends on what’s causing your nausea.
Getting The Better Of Gerd
GERD is a problem of modern life. Smoking, poor eating habits, obesity, alcohol abuse, and stress all fuel the fire of heartburn. A little heartburn from time to time is no big deal but persistent GERD can lead to serious complications. Fortunately, this modern problem can be solved with old-fashioned lifestyle changes, modern drug therapy with PPIs or other agents, and new surgical options.
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Side Effects Of Nausea Medicine
Common side effects of anti-nausea medication include:
Most medications to treat nausea are safe, Devine says, but there are cases where anti-nausea medication may not be a good idea. Some common anti-nausea medications, like those acting on dopamine and serotonin receptors, can affect electrical rhythms of the heart.
These medications are typically not recommended for people with a history of heart conditions or those on other medications with potential side effects of heart rhythm abnormalities.