Friday, April 12, 2024

Does Zofran Help With Diarrhea

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What Drugs Interact With Ondansetron And Dramamine

When to use Ondansetron, also known as Zofran | Must Know Medications (Nursing School Lessons)


Ondansetron and apomorphine should not be used together due to sudden lowering in blood pressure and loss of consciousness.

Phenytoin, carbamazepine, and rifampin can increase ondansetron elimination and decrease blood levels, possibly lowering the effects of ondansetron.

Dronedarone can increase blood levels of ondansetron by reducing its breakdown in the liver. This may increase side effects of ondansetron. This combination may also increase the risk of abnormal heartbeats.


Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctors approval.

Some products that may interact with this drug include antihistamines applied to the skin such as:

  • narcotic pain relievers .
  • Check the labels on all your medicines because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

    This medication may interfere with certain laboratory tests , possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

    What Happened To Mylanta

    For many years, especially in the 1990s, Mylanta was a popular product used to alleviate the symptoms of heartburn. However, in 2010, the over-the-counter antacid was voluntarily recalled due to traces of alcohol being found in the product.

    According to the manufacturer, Johnson & Johnson, the product was recalled so it could be relabelled with better accuracy, not because of any risk to alcohol absorption or adverse effects.

    In 2016 Mylanta was reintroduced to the market and deemed safe to use as an antacid.

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    Interactions Between Cymbalta And Other Medications

    Cymbalta may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements that you are currently taking. The list below does not include all possible drug interactions with Cymbalta . Please note that only the generic name of each medication is listed below.

    Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

    • Bromopride

    I took Cymbalta mostly for GAD about a decade ago. It wasnt generic and I had to switch because of how much it cost. Along with therapy sessions, it helped my depression quite a bit. Ive been having depressive symptoms more recently so I went back on Cymbalta 5 weeks ago. Its been a godsend and within a week, friends said my voice seemed happier and more in control. My doctor increased my dosage from 30 mg to 60 mg, and so far, Im getting my life back.

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    Ondansetron May Interact With Other Medications

    Ondansetron orally disintegrating tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

    To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs youre taking. To find out how this drug might interact with something else youre taking, talk to your doctor or pharmacist.

    Examples of drugs that can cause interactions with ondansetron are listed below.

    What Other Drugs Will Affect Zofran

    Does Zofran Help Diarrhea

    Zofran can cause a serious heart problem, especially if you use certain medicines at the same time, including antibiotics, antidepressants, heart rhythm medicine, antipsychotic medicines, and medicines to treat cancer, malaria, HIV or AIDS. Tell your doctor about all medicines you use, and those you start or stop using during your treatment.

    Taking ondansetron while you are using certain other medicines can cause high levels of serotonin to build up in your body, a condition called “serotonin syndrome,” which can be fatal. Tell your doctor if you also use:

    • medicine to treat depression

    • medicine to treat a psychiatric disorder

    • a narcotic medication or

    • medicine to prevent nausea and vomiting.

    This list is not complete and many other drugs can interact with ondansetron. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

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    Are Ondansetron And Dramamine Safe To Use While Pregnant Or Breastfeeding


    There are no adequate studies of ondansetron in pregnant women to determine its safe and effective use during pregnancy.

    It is not known whether ondansetron enters breast milk therefore, it is best to be cautious before using this medication while breastfeeding.


    During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

    This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breastfeeding.

    When Zofran Is Given To Children

    While many practitioners find Zofran helpful in the emergency room at preventing and treating vomiting from gastroenteritis, your pediatrician might not prescribe it on an outpatient basis. The current practice guidelines, including those from the American Academy of Pediatrics, don’t recommend using medications to stop vomiting.

    There are no research studies supporting that it works in this situation as all of the studies have been done in an emergency room setting. If further research supports it, maybe doctors will use it more for kids with the stomach flu.

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    Warnings For Other Groups

    For pregnant women: There havent been enough studies done in humans to be certain how ondansetron might affect a fetus when the mother takes it. Research in animals has not shown a risk to the fetus. However, animal studies do not always predict the way humans would respond.

    Talk to your doctor if youre pregnant or planning to become pregnant. This drug should only be used in pregnancy if clearly needed.

    For women who are breastfeeding: Ondansetron may pass into breast milk and may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication.

    For seniors: The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, a higher amount of a drug stays in your body for a longer time. This raises your risk of side effects.

    For children: This medication has not been studied in children younger than 4 years. It should not be used in children of this age range.

    All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

    • your age
    • how severe your condition is
    • other medical conditions you have
    • how you react to the first dose

    Help For Nausea With Endometriosis

    Ondansetron (Zofran) Overview | 4 mg, 8 mg tablets and ODT Uses, dosage and side effects

    Many with endometriosis suffer from the constantdebilitating symptom of nausea. But whyshould this disease cause nausea?

    Nausea can be so bad for many that it can cause vomitingon a regular basis. For some the nausea is only really acute just before andduring menstruation your body is flooded with negative prostaglandins just beforemenstruation and this can cause nausea. For others the nausea can be at any time of the month.

    Pain and nausea connection

    There is a strong relationship between pain and nausea, notonly with endometriosis, but with many other diseases that cause pain. The constant stress of being in pain somehowincreases the pain perception in the brain. Additionally, the gut is well knownfor being the second brain, so the emotional effects of constant pain alsoaffects functions of the gut. This canhave the knock-on effect of causing nausea and gastrointestinal distress.

    Neurotransmitters and pain

    Many neurotransmitters are produced in the gut. Some neurotransmitters are responsible forthe transmission of pain signals, while others help to block pain. Research is still ongoing into therelationship between neurotransmitters and pain, but looking after your guthealth can help to improve brain health and your emotions as well as help withpain.

    Diet and nausea

    Many in the endometriosis community who advise about diet onlygo as far as suggesting what diet changes to make to help with nausea without joiningthe dots of the complex chemistry that is involved.

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    What Is Ondansetron 4 Mg Used For

    Ondansetron is used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery. Ondansetron is in a class of medications called serotonin 5-HT3 receptor antagonists. It works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting.

    Rated For Alcohol Dependence Report

    This is a miracle drug. Without it I would not be able to eat due to chronic nausea. For me the headaches are minimal and a couple of aspirin take care of it The trade-offs between weighing less than 100 pounds because I cant hold food down, vrs being nauseous 24 seven versus an occasional headache, the benefits far outweigh the negatives Other than constipation and the occasional headache which again, an aspirin takes care of, this drug has had no additional side effects

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    Does Ondansetron Make You Sleepy


    Similarly, you may ask, what are the side effects of ondansetron?

    The most common side effects of ondansetron are:

    • Headache.
    • Hiccups.
    • Flushing.

    Subsequently, question is, does Zofran make you sleepy like Phenergan? Zofran is an antiemetic and selective 5-HT3 receptor antagonist and Phenergan is an antihistamine. Side effects of Zofran and Phenergan that are similar include dizziness, drowsiness, constipation, and blurred vision.

    Also to know is, how long does it take for ondansetron to work?

    Ondansetron works in the stomach to block the signals to the brain that cause nausea and vomiting. The standard tablets that are swallowed will start to work within half an hour to 2 hours. Medicines generally work faster on an empty stomach, an hour before food or 2 hours after.

    Does Zofran have a sedating effect?

    Ondansetron is an anti-nausea medication and promethazine is a phenothiazine. Side effects of ondansetron and promethazine that are similar include drowsiness and sedation, constipation, and dizziness.

    Interactions That Can Make Ondansetron Less Effective

    Does Zofran Help Diarrhea

    Taking these drugs with ondansetron can make ondansetron less effective. This is because the amount of ondansetron in your body may be decreased. Examples of these drugs include:

    • Anti-seizure drugs, such as phenytoin or carbamazepine. Your doctor may switch you from ondansetron to a different drug if needed.
    • Tuberculosis drugs, such as rifampin, rifabutin, or rifapentine. Your doctor may switch you from ondansetron to a different drug if needed.

    Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare professional about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

    This drug comes with several warnings.

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    What Are Reasons I Shouldnt Take Zofran Odt

    You should not take Zofran ODT if you have a known allergy or sensitivity to the medication or any of its ingredients.

    Patients with a genetic condition called phenylketonuria should be cautious taking Zofran ODT. Zofran ODT contains phenylalanine .

    You should not take Zofran ODT if you take a medication used to treat advanced Parkinsons disease called Apokyn .

    Ondansetron Relieves Irritable Bowel Syndrome Symptoms

    Gale ScottInternal Medicine World Report

    Patients with irritable bowel syndrome with diarrhea suffer not only the pain and discomfort of frequent loose stools, but fear of incontinence. For many patients, that results in panic and anxiety.

    Patients with irritable bowel syndrome with diarrhea suffer not only the pain and discomfort of frequent loose stools, but fear of incontinence. For many patients, that results in panic and anxiety.

    In an effort to address those concerns, a team at Nottingham Diseases Centre, University Hospital, Nottingham, UK, conducted a study of ondansetron vs. placebo in a group of 120 IBS-D patients. The group taking ondansetron got significant relief from their debilitating symptoms, Klara Garsed and colleagues reported in Gut .

    Compared with placebo, ondansetron significantly improved stool consistency, patients experienced fewer days with urgency, less frequent defecation, and less bloating. Pain associated with IBS-D did not change significantly.

    Overall, 65% of patients reported symptom relief with ondansetron, while only 14% getting the placebo reported relief.

    In the crossover study, participants received 5 weeks of oral placebo treatment and 5 weeks of ondansetron 4 mg tablets with a 2-3 week washout period in between each treatment period.

    Loperamide was allowed as a rescue medication but needed to be discontinued for the final 2 weeks of the period. Patients kept track of their symptoms with daily diaries.

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    Are There Other Nausea Management Medicines Besides Zofran That Kids Can Take

    In almost 8 years of working in an emergency room, there have been two main prescription medicines Ive administered for nausea and vomiting. The most common one was Zofran. It really works well!

    Another similar medicine is Phenergan. Its more commonly prescribed to adults, so perhaps youre familiar with it. We mainly gave it to teenagers with migraines and migraine-induced nausea.

    However, it isnt usually used with small children. In fact, the FDA states it should not be used at all for children under the age of two. Thats because Phenergan has the tendency to make you sleepy and can mess with your breathing to a small degree. Unfortunately, that small degree in small children is a big deal. So, Phenergan is a no-go for most kids.

    In other words, Zofran is usually the first line of prescription medicine. However, if you dont have access to Zofran, there are some natural and holistic ways to manage vomiting. And these dont require a prescription.

    • One is by practicing deep breathing and mindfulness. This works better with older kids who can be calmed down when ill in other words, you may need to combine this with another idea!
    • There are also certain essential oils that help manage nausea and vomiting, especially spearmint and winter mint.
    • Check the over-the-counter area at your local pharmacy for pharmacist-recommended nausea remedies. One weve used and loved is quite literally flavored sugar water. And its delicious.

    What Other Information Should I Know

    Chemotherapy: Nausea, Vomiting, Diarrhea, Constipation

    Keep all appointments with your doctor.

    Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

    It is important for you to keep a written list of all of the prescription and nonprescription medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

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    Treating A Stomach Bug

    Dehydration may become a serious concern for people who have the stomach virus. Watch for the symptoms of dehydration. You should seek medical attention if any of these symptoms occur.

    Make sure you get plenty of fluids. Adults can drink fluids such as Gatorade with electrolytes, and children can also drink fluid replacement solutions such as Pedialyte. These drinks coupled with water will help restore the bodys hydration balance. For best results, drink a few sips every half hour to an hour.

    Dont drink sugary drinks like Kool-Aid or sodas, as these liquids dont replace lost electrolytes. Taking in ice chips or drinking plain water is another good option for staying hydrated.

    Once you feel ready to eat again, give your stomach a break by slowly introducing bland foods into your diet. These may include:

    • cereals
    • symptoms of dehydration, including fatigue and extreme thirst
    • symptoms of botulism
    • symptoms of food poisoning after visiting a developing country

    If you have a mild case of food poisoning, it may respond well to rest and fever-reducing medications. If you have a severe case, you may need to be admitted to the hospital for intravenous fluid hydration. If you have severe bacterial food poisoning, your doctor may prescribe an antibiotic.

    Your doctor will review your symptoms and run tests to determine the best course of action.

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    Baclofen For Treating Anxiety And Alcoholism

    The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
    First Posted : December 18, 2012Results First Posted : August 16, 2017Last Update Posted : September 18, 2017
    • Study Details


    Baclofen is a drug used to control muscle stiffness in people with neurological diseases. Some studies suggest that baclofen may reduce alcohol craving and use. It helps to reduce anxiety in alcoholics, which in turn can help to reduce cravings. Researchers want to see if baclofen can be a safe and effective treatment for alcoholics who have high anxiety levels.


    To see if baclofen is safe and helpful for people who have alcoholism and high anxiety levels.


    • Individuals between 21 and 65 years of age who have been diagnosed with alcoholism and anxiety issues.
    • Participants must not be taking anti-anxiety medication.


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    What Are The Side Effects Of Ondansetron And Alosetron


    Some individuals may develop abnormal heart rate and rhythm.



    Alosetron was approved for marketing by the FDA in February, 2000, but was withdrawn from the market in November, 2000, because of serious, life-threatening, gastrointestinal side effects. In June 2002, it was approved again by the FDA for marketing but in a restricted manner as part of a drug company-sponsored program for managing the risks associated with treatment. Use of alosetron is allowed only among women with severe, diarrhea-predominant, irritable bowel syndrome who have failed to respond to conventional treatment for IBS.

    Common side effects

    The most common side effect of alosetron is constipation. One-quarter to one-third of patients may develop this side effect. Severe constipation or intestinal inflammation caused by poor circulation of blood are rare but life-threatening, may require surgery, and may cause death. Therefore, alosetron must be discontinued immediately, and immediate medical attention should be sought if constipation or the signs of ischemic colitis occur.

    Other important but less common side effects include:

    • nausea,

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